About this item: 20.500.12592/d2zqtg
The Indian Journal of Medical Research October 1928
1928
Summary
In order to make plain the meaning of some of the details in the tables given above a few explanations are necessary as regards the technique employed in the experiments and the exact meaning of some of the terms used. [...] The figures in column 5 representing the probable number of feeds by infected flies have been obtained in the case of the mice (Table by totalling up the results of all dissected flies in the three series and applying the percentage infection so obtainedTABLE I. Showing the details of transmission experiments with P. argentipes and white mice. [...] The duration of the experiments in the case of the mice and hamsters varied from a maximum of 470 days to a minimum of 43 days with an average duration of 246 days. [...] In the case of the human volunteers where the degree of susceptibility of the human subject and the limits of the incubation period of kala-azar are not really known the number of experiments is too small to justify us in drawing any conclusions. [...] SINCE the discovery (Knowles Napier arid Smith 1924) that Leishmania donovani flagellates in the midgut of Phlebotomus argentipes and the subsequent elucidation by the Kala-azar Commission of the life-history of L. donovani in P. argentipes (Shortt Barraud and Craighead 1926) the attention bestowed upon this insect has left little leisure for the investigation of the older theory of infecti
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